Sentence examples for mutation need to from inspiring English sources

In the evolutionary context, on the other hand, another type of robustness, robustness to mutation need to be considered.

Our findings with regard to DNMT3L methylation and KRAS mutation need to be investigated further as recently aberrant promoter hypomethylation of DNMT3L has been linked with cervical cancer tumorigenesis [60].

Therefore the frequencies of nonsynonymous mutation need to be computed from the given frequencies of independent nucleotide mutation.

54 Female patients with encephalopathy who test negative for SCN1A mutation need to be tested for PCDH19.

Patients with the same GATA2 mutation need to be investigated further and experimental models will help to better understand the molecular defect(s) leading to PAP.

After this, the first crossing task is given, in which a second and third chromosomal recessive lethal mutation need to be combined into one double-mutant stable stock using a multiple balancer stock as a further aid.

If this is not the case, a new set of primers for the second mutation needs to be designed and used.

This technology has wide_ranging therapeutic potential and could lay the groundwork for treating diseases where a gene's expression needs to be altered (such as turning down CCR5 in HIV), or where a mutation needs to be repaired (such as sickle cell diseases or hemophilia).

The main advantage of this procedure is its rapidity as mutants can be easily obtained in less than a week if the 3-step PCR procedure is used, or in less than three days if the mutation needs to be transferred from one strain to another.

The mechanism for how α3 connexin leads to a dosage-dependent inhibition of nuclear cataract induced by γB-crystallin S11R mutation needs to be further investigated.

The significance of this mutation needs to be evaluated.