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Therefore, PP2A-Rts1 is not required for sister kinetochore biorientation and the sgo1-3A musttion must disrupt functions of Sgo1 other than its association with PP2A-Rts1.
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And I said TCS must disrupt itself and look at serving the small and medium businesses.
To observe a large conformational change in an RNA, the mutation must not only disrupt an existing base-pair, but also favor a completely alternative base-pairing network.
The authors suggested that the Tph2 mutation must be very tightly linked to the gamma-TMT locus on LG 8 and may disrupt regulatory sequences.
The mutation must be functionally relevant.
Introducing a proline mutation to disrupt this putative helix drastically increases the autolytic properties of IS1.
This mutation may disrupt an inactive conformation of BRAF kinase.
We next tested whether this mutation would disrupt Rab6 binding.
Null mutations (including missense mutations disrupting the tetramerization domain) and the remaining missense mutations displayed an intermediate aggressive clinical phenotype.
Unlike the other mutations occurred at residues in the conserved Greek-key motifs, the S228P mutation did not disrupt the hydrophobic core directly.
To win early in the down, you must immediately disrupt the offense's timing and rhythm.
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CEO of Professional Science Editing for Scientists @ prosciediting.com