Sentence examples for mutation must affect from inspiring English sources
A single nucleotide change can be sufficient to transform a proto-oncogene into an oncogene that induces cell transformation, whereas an inhibiting mutation must affect the two alleles of a tumor suppressor gene to favor transformation [ 61].
Rather, the NLS mutations must affect a step downstream in the infection cycle, probably during RNA replication or transcription.
For many independent axes to emerge, mutations must affect differentially the different traits, such that no absolute correlation exists among them.
To explain the observed frequency of pleiotropy among D. serrata expression traits, at least some mutations must affect a substantial number of traits (>70); we cannot distinguish between a distribution with few very large modules and many relatively small ones vs. a more normal distribution with module sizes distributed about a fairly large mean (∼70).
The mutation, therefore, must affect mtPAP function directly, because the N478 region does not contribute to the dimer interface (23).
Instead, the mutation must be affecting some other property that limits spontaneous nucleation in wild-type αβ-tubulin.
I guess it must affect you eventually.
2) The predictor must affect the outcome.
This frequency of statistically supported covariance implied that at least some mutations must pleiotropically affect a substantial number of traits (>70; 0.6% of all measured traits).
