Sentence examples for mutation modifies the from inspiring English sources

This finding indicates the C57BL/6J strain background, and possibly the Nnt mutation, modifies the Bcl2l2 mutant phenotype.

This study shows how the over-expression of the G93A-SOD1 gene mutation modifies the molecular response to a mild mechanical compression in the spinal cord tissue from a pre-symptomatic rat.

In this study, we have investigated by large-scale gene expression analysis how the G93A-SOD1 gene mutation modifies the acute molecular response to a mild compression injury in a pre-symptomatic rat.

For instance, kinetic analyses have indicated that the R30K mutation, in combination with the S291G, enhances AChE2 insensitivity in the beetle [ 24], whereas a second (I392T) mutation modifies the AChE2 to be susceptible to organophosphates (azinphosmethyl in particular).

Since the patient carrying the S59P mutation was responsive to IL-1Ra but not to anti-TNF therapy, the aim of this study was to verify whether this mutation modifies the cell signaling, in particular in the NF-κB pathway, after TNF and IL-1β stimulation.

A mouse model with mutations in both CYP1B1 and Tyr was also developed and revealed that Tyr mutation modifies the phenotype associated with inheritance of mutant orthologs of CYP1B1 and Foxc1, both of which have been shown to be involved in human angle-closure glaucoma [ 96, 97].

The S228P mutation modified the refolding pathway of βB1-crystallin by affecting the formation of the dimeric intermediate but not the monomeric intermediate.

For example, does the γ/ε-fc mutation modify the nerve-independent prepatterning process, nerve/muscle contact formation and stabilization, the dispersion of non-synaptic AChR aggregates, and the overall development of muscle fibers?

Biophysical studies indicated that the mutation modified the structure of both βB1-crystallin and βB1/βA3-crystallin, which is consistent with the fact that Ser129 is close to the domain and subunit interfaces (Fig. 2F) (Van Montfort, et al., 2003).

Among the 44 nonsynonymous mutations, when we focused on CMS-G totalizing 23 nonsynonymous mutations, one mutation generated a premature stop codon in exon2 of cox2, whereas one mutation modified the stop codon of nad9, resulting in a longer coding sequence of 42 bp, as previously described by our team (Ducos et al. 2001).

Recently, various genes have been identified whose mutations modify the life span of certain animals.