Sentence examples for mutation might work from inspiring English sources

Exact(1)

Nonetheless, the man has been free of the virus for 20 months even though he is not using antiretroviral drugs, and the success in his case is evidence that a long-dreamed-of therapy for AIDS — injecting stem cells that have been genetically re-engineered with the mutation might work.

Similar(59)

Another suggestion, stated explicitly by Ho et al. (2009), is that mutations might work in different ways to change a critical interactor that is not necessarily a substrate.

Rieger notes that mutations in RNase L might work in concert with other mutations to cause the disease, which could explain why mice lacking RNase L don't develop cancer.

Thus, a loss of function on the one hand is a gain of function on the other, as a hairless mutation, a loss of function, might work as a gain of function as a bipedalism inducer.

Therefore, whereas the study of Awatade et al. (2015) confirms the feasibility of exploring how CFTR might work with different mutations and with the best front-runner CF correctors, if the future for the disease is to tailor an appropriate pharmaceutical product, then it will require a great amount of effort to correlate drug effect with specific CF mutations.

However, a similar approach might work for some other mutations.

Dr. Fair approached Dr. Wang, who gave him the parent preparation, SPES, and suggested that it might work against tumors that had a p53 mutation.

So even though a drug might work well for patients whose tumors have a particular mutation, when the drug is used for a broader population, it shows only a small effect.

Though the details are unclear, aspirin might work in several ways: by reducing inflammation, slowing mutations in cells, and preventing cancer cells being spread around the body on blood platelets.

ATLL has a higher mutation rate than other blood cancers, so the researchers theorized that PD-1 immunotherapy might work in this malignancy.

The idea that the drugs might work against something like hypercalcemic ovarian cancer, which is fueled by just one genetic mutation, just made no sense.

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