Sentence examples for mutation measurements from inspiring English sources

Although several correlated mutation measurements yield reasonable accuracy for intramolecular contact map prediction, the accuracy level drops in intermolecular contact prediction [ 14].

Since samples from cases were obtained after cancer treatment, DNA damage due to therapy with radiation or chemotherapeutic drugs is a potential confounder favoring higher mutation measurements in cases compared to controls.

Additionally, in the particular case of the HPRT assay, cord blood mutation frequencies (M f ) measured at birth are approximately 10-fold lower than that predicted from age-dependence data in older children and adults, with a correspondingly low variance, such that cord blood HPRT mutation measurements should be uniquely sensitive to inductive effects [ 20].

Mutation measurements are complicated by a process called 'field cancerisation', by which carcinogen exposure of a larger field of cells (e.g. oral or bronchial epithelium) leads to groups of related, but histologically normal, cells that spread to cover a large epithelial surface (Slaughter et al, 1953).

The authors wish to thank Prof Fumio Endo, Dr Kimitoshi Nakamura (School of Medicine, Kumamoto University) for completing enzyme activity measurements, and Prof Yoshikatsu Eto, Prof Toya Ohashi, and Dr Masahisa Kobayashi (The Jikei University School of Medicine) for performing gene mutation measurements.

In order to determine the effects of a mutation, measurement of physiological variables, such as biopotentials, is often necessary.

We are conducting experiments to evaluate the sensitivity of hprt mutation measurement in the nonhuman primate, the cynomolgus monkey.

In our study, field cancerisation may lead to an apparent increase in the mutation measurement due to selective outgrowth of an otherwise normal cell clone carrying a mutant microsatellite sequence.

Next generation sequencing (NGS) techniques are widely used to explore diverse areas in the study of cancer, including identification of driver mutations, measurement of tumor heterogeneity, investigation of genetic susceptibility, and characterization of mutational motifs to better understand underlying mutational processes.

Thus, additional measurement of the frequency or prevalence of the quintuple mutation alongside measurements of both the dhfr and dhps mutations may guide policy makers in deciding where to implement SP-IPTi.

We found that GFP as a reporter, combined with a drug selection marker, gave the most consistent and convenient mutation rate measurements.