Sentence examples for mutation may represent from inspiring English sources

Furthermore, the overall incidence of Ki-ras mutations in the hyperplasia specimens (16%) was similar to the incidence detected in carcinomas (18%), indicating that ras mutation may represent an early event in a subset of endometrial carcinomas.

Within a family, carrying a risk mutation may represent risk for a constellation of developmental phenotypes.

Indeed, this mutation may represent the initial stages of evolutionary divergence between these 2 genes.

This mutation may represent a candidate frequent mutation in the Italian population.

Finally, bladder cancers harboring a beta-catenin mutation may represent aggressive biological behavior with enhanced proliferating activity [ 44].

We thus hypothesised that KRAS genome amplification, rather than mutation, may represent a predominant mechanism for KRAS activation in gastric cancer.

The development of epithelial cancers requires multiple mutations (Fisher, 1958), and the stepwise accumulation of these mutations may represent an inherent mutator phenotype (Loeb, 1991).

It has been postulated that these mutations may represent a fingerprint of aromatic amine which are the most potent class of bladder carcinogens in tobacco smoke.

Using base editors to directly repair point mutations may represent an efficient and highly specific alternative.

Thus, in our series, INF2 mutations were responsible for 16% of all cases of autosomal dominant FSGS, with these mutations clustered in exon 4. Hence, screening for these mutations may represent a rapid, non-invasive and cost-effective method for the diagnosis of autosomal dominant FSGS.

Thus, enhanced microtubule polymerization and reduced dynamic instability caused by tubulin mutations may represent a survival mechanism against microtubule de-stabilizing compounds.