Sentence examples for mutation may modify from inspiring English sources

Whether the presence of a mutation may modify the glycoform ratio of PrPc in the human brain is poorly documented.

In addition to allosteric regulation, the putative driver mutation may modify protein-protein interactions.

In this case, the mtp5 mutation may modify subcellular metal concentration(s) adequately to compensate for the presumed transport defect in iar1 seedlings, but not alter levels enough to cause toxic metal accumulation that would increase sensitivity to exogenous metals.

Since temperature affects the stability and activity of proteins [ 50- 52], rpoB mutations may modify the stability and/or activity of RNAP at high temperatures.

Given that lead is carried by these same iron transporters and receptors, it is possible that functional perturbations in the HFE protein resulting from HFE C282Y gene mutations may modify placental lead transfer.

Even in the absence of genomic instability, changes of chromatin organization induced by changes of transcriptional activity may modify gene mutation probability as it has been shown that transcriptional active DNA regions may display more efficient repair of base damage and less efficient repair of DNA breaks (Bailey and Bedford, 2006).

The presence of co-occurring mutations involving critical cancer genes may modify the clinical response to single-agent targeted therapy.

Since AHI1 and CEP290 appear to be in the same pathway through their interaction with rab8a, mutations in one of both genes may modify a phenotype caused by the other (Kim et al., 2008; Tsang et al., 2008; Hsiao et al., 2009).

The clinical impact of p53 mutations in breast cancer remains uncertain, especially where p53 isoforms may modify the effects of these p53 mutations.

The attenuation of the resulting virus is assessed in a relevant model, and if it is either over- or under-attenuated, then the mutation may be modified or additional mutations may be added.

However, there is circumstantial evidence that the cancer risk conferred by BRCA2 mutation may be modified by other genetic or environmental factors.