Sentence examples for mutation may affected from inspiring English sources

There seems to be a selected mutation specific to British breeds (i.e. Shorthorn, Angus, Murray Grey and Hereford; Additional file 3: Figure S13) and, although ASIP mutations are unlikely to affect coat colour in these cattle, the locus may have affected coat colour in ancestors without the MC1-R mutation or the mutation may affected other traits such as fatness and homeostasis [ 45].

In this study, the molecular dynamic simulation was used to investigate the possible mechanisms by which F1174V mutation may affect the structure and activity of ALK kinase domain.

Because the mutation may affect the polymerization rates and the affinity to the nucleotide substrate, fidelity is calculated as the ratio of kpol/KD for the correct NTP to kpol/KD for the incorrect substrate (Wong et al., 1991).

Though there are mechanisms by which synonymous mutation may affect protein function, they are more likely to be effectively neutral than non-synonymous mutations [14].

In fact, co-immunoprecipitation studies using brain lysates suggest that the M105I mutation may affect the αSNAP/SNARE complex interaction [14].

This mutation may affect one of these fusion steps and thus modify the fusion activity of S protein and syncytia formation.

While there are no epitopes described overlapping this position, that OP428 could recognize, the mutation may affect processing of the EL9 epitope.

Although this suggests that the p.A222V mutation may affect fertility, the authors observed that the homozygous prevalence rate in subfertile and fertile men was not significantly different.

Further studies will be required to understand the mechanisms by which the glp-4 mutation may affect DAF-16-dependent and –independent immune responses against pathogen infection.

It is likely that at the protein level, a given point mutation may affect frataxin stability reducing its level in PBMCs, as suggested by previous studies [22].

Therefore, the DIA1R-S24P mutant is still expected to translocate to the secretory pathway, but the mutation may affect the size of the mature protein, with resulting impact on structure and function.