Sentence examples for mutation load on from inspiring English sources

The effect of a deleterious mutation load on the fate of an antigenic mutant.

For most of the remaining analyses, we focused on the effects of mutation load on ER+ breast cancer.

It is interesting to note that there seems not to be any trivial dependence of the average mutation load on the number of stop codons in the genetic code.

This approach is a useful first step to characterise the nature of mutation load on an individual level, and may have important implications in studying human fitness and disease.

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For example, based on the mutation load of the S-signature, the LUAD samples shown in Figure  4 with an unknown smoking status are implied to be heavy or light smokers rather than never smokers.

This distribution of deleterious mutation loads on the simulated phylogeny is consistent with the excess number of non-synonymous substitutions on external tree branches that was found for human influenza A/H3N2 (Fitch et al., 1997; Pybus et al., 2007) and arises because deleterious mutations contribute a substantial fraction of the fitness variance in the viral population.

In addition, the effects of female preference on male gamete mutation load depended on mutation rate.

Figure 6A (which shows the deleterious mutation load distributed on viral lineages present in the phylogeny) further illustrates that deleterious mutations contribute substantially to fitness variance.

One advantage of the cloning and the single molecule PCR techniques is that the mutation load is calculated based on the exact number of base pairs sequenced, which can be simply counted; however, the RMC assay is reliant upon quantitation of exact starting copy number prior to digestion with Taq1α, which is dependent upon accurate quantification of DNA concentrations.