Sentence examples for mutation load in the population from inspiring English sources

If the mutation load in the population is M, the probability of any locus being mutated will be M/10, and the probability of carrying two mutated alleles of any given gene will be (M/10 2 = M.10-8 and hence the effect on fertility would be (1- M.10-8)10,000 overall since the threat applies for every single one of the 10,000 essential genes.

The resulting population genetic architecture is characterised by genetic homogenization in small geographical scale, higher individual fitness, increased heterozygous mutation load in the population and local gene flow.

Upon harvesting, we recorded the fertility and found that 9.6% of the M2 plants from the 0.3% population and 27.9% of the M2 plants from the 0.4% population failed to set seeds suggesting a higher mutation load in the 0.4% population.

Thus, the mutations detected represent an underestimate of the total somatic mutation load in the tumor mtDNAs.

Indeed, we have seen that the mutation load in a population is inversely related to the degree of inbreeding in this population, and the existence of species thus appears to rely on a fragile, metastable equilibrium, which I find very appropriate to represent in the context of the Yin Yang symbol to evoke the balance between degrees of inbreeding and outbreeding.

Recent work has indicated, however, that if a fraction of mutations are beneficial rather than deleterious, the average mutation load in a population can be maintained indefinitely over time (Goyal et al., 2012).

The fern mutagen bioassay is based upon the detection of numerous categories of post-zygotic mutation load in natural fern populations.

We found a significant decrease in mutation load in populations in which females exhibited a preference based on male age.

If we imagine that the mutation load in such a large population had reached 40, and that the reduced numbers of individuals causes the inbreeding coefficient to rise to 0.03 in the remaining population, this will result in only 30% of viable zygotes.

To obtain insight into the mutation load in specific genes ensuing differentiation and proliferation in SCs, we mapped our mutations to expression data generated by the FANTOM5 project28.

Redfield [ 19] modelled the effect of elevated male mutation rates on the mutational load in infinite sexual populations and compared the results with those from infinite diploid asexual populations.