Sentence examples for mutation limited in from inspiring English sources
There is mounting evidence that adaptation is not mutation limited in many species, even when it requires a specific nucleotide mutation in the genome (Messer and Petrov 2013).
The much lower prevalence of RET/PTC rearrangement and RAS mutation limited their use in FNA diagnosis.
In this case, adaptation is not mutation limited during population maxima and is mutation limited during population minima.
However, the number of patients with a single CEBPA mutation is limited in our collection of patients, and larger series are needed to definitively assess its prognostic significance.
Perhaps, but we also cannot rule out the possibility that I26A mutation allows limited in vivo interaction with one of 38 enzymesmes [ 13] not previously detected in prior, albeit very rigorous, studies of BRCA1 binding [ 7, 14] and that such interaction is sufficient for ubiquitination of some BRCA1 substrates.
In higher eukaryotes the accumulation and spread of mutations is limited in two primary ways: through p53-mediated programmed cell death and cellular senescence mediated by telomeres.
However, published data on KRAS and BRAF mutation status is limited in GC and has not been compared between GC from different geographic regions.
The much lower frequency of RET/PTC rearrangement and RAS mutations limited their utility in FNA diagnosis.
Moreover, although their results showed that the methylation level affected the mutation rate, their investigation limited in the intronic regions only, and the mutation pattern in other genomic regions remained unclear.
Our analysis suggests that DNE TP53 mutations, which are albeit limited in general, differ with respect to specific mutations.
Because studies of prokaryotic mutation rates are still limited in taxonomic scope, we scoured recent literature to apply a range of plausible rates (1 × 10−7 to 1 × 10−9 substitutions per synonymous site per year) (Drake 1991; Ochman et al. 1999; Kuo and Ochman 2009; Wielgoss et al. 2013).
