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Nonetheless, the Asp390Gly mutation leads to loss of function leading the pathological condition.
Wakabayashi, N. et al. Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.
Our mutation leads to changes in the dynamics of the sleep homeostasis.
This mutation leads to aberrant synaptic transmission at the neuromuscular junction.
In Duchenne muscular dystrophy (DMD), dystrophin mutation leads to progressive lethal skeletal muscle degeneration.
This single mutation leads to a shortened core protein precursor with a calculated molecular weight of 158 kDa.
The paucity of lymph node T cells (plt) mutation leads to a loss of CCL21 and CCL19 expression in secondary lymphoid organs.
A stem cell model of a lethal brain tumor in children shows how a recurrent histone mutation leads to cancer.
Thus the I214V mutation leads to increased internal dynamics.
This mutation leads to a wider distribution of cell lengths but not to altered growth rates.
First, the GneM712T/M712T mutation leads to a partial down-regulation of ST3Gal5 mRNA synthesis.
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