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Next, in order to determine the role of Azot's EF hands, we generated and overexpressed a mutated isoform of Azot (Pm4Q12) carrying, in each EF hand, a point mutation known to abolish Ca2+ binding (Maune et al., 1992).
The donor of the transplanted bone marrow also carried a specific mutation known to interfere with HIV's ability to infect white blood cells.
For example, Dr Ding discovered that the BRAF mutation, known to be present in about half of melanomas, was also found in other cancers, such as 7% of lung adenocarcinomas and 4% of colon and rectal carcinomas.Even though there remains more basic science to be explored, the genetic approach points to a new way of matching patients to drugs.
If one of the parents carries a mutation known to cause an autosomal dominant inherited disease, whether that parent is clinically affected or not, there is a 50 percent risk that each future child will inherit the mutation and therefore may be affected.
A UL97 mutation, known to confer GCV resistance, was found in two isolates from a renal transplant patient.
While investigating a gene mutation known to affect organ development in chickens, Matthew Harris of the Max Planck Institute in Tübingen, Germany, noticed sharp protrusions on the jaw of a 16-day-old embryo.
Similar(16)
There are 196 mutations known to affect the cystic fibrosis gene, CFTR.
It will be the first comprehensive center to focus on a specific set of mutations known to cause cancer.
So we capture all the [genetic material floating in our blood] rather than fixating on a few mutations known to be associated with cancer".
To optimize hydrogen production, we combined in a single strain several mutations known to enhance hydrogen production in anoxygenic phototrophic bacteria.
Q: This H1N1 does not have the genotypic mutations known to cause resistance to drugs that inhibit neuraminidase [the "N" in H1N1].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com