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Although most of the interest in 8-oxoG has understandably been in its direct involvement in DNA mutation, it was also found in vitro that RNA polymerases could frequently misincorporate an A opposite 8-oxoG during the process of transcription (Chen and Bogenhagen 1993; Viswanathan and Doetsch 1998; Doetsch 2002).
Since the introduction of an NcoI site in the 5´primer causes a mutation it was designed so that the initial MakA residue, Met, was mutated to Gly keeping the sequence from the second residue intact.
While it was Gessen's misfortune to have inherited her mother's cruel mutation, it was her good luck — and ours — that she also inherited her mother's storytelling grace and critical dexterity (Yolka Gessen was a writer and a translator).
And it's not a chance mutation, it was something necessary.
Since Srs5 was also a semi-dominant mutation, it was likely caused by incomplete conformation of the tubulin complex.
But also blood cells bear the mutation (it was found there).
Similar(46)
But like any language, jazz accommodates mutation; it's subject to the whims of usage.
Because all felines — from domestic cats to lions — have an identical mutation, it is likely that the sweet-receptor gene became inactive in their common evolutionary ancestor.
The researchers' work suggests that in the worms with the genetic mutation, it's not just that there are fewer proteins around, but that there are fewer of the unfolded ones.
"Although much is known about mutation, it is still largely a "black box" relative to evolution.
Since the technology involves using biocatalyst developed by adaptive mutation, it is not subject to government regulations of GM products.
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