But also blood cells bear the mutation (it was found there).
The devil cancer genome contains more than 17,000 somatic base substitution mutations and bears the imprint of a distinct mutational process.
Of these, most contained single mutations: eight had either H3 A7V or H3 A7T mutations, seven had an H3 T6I mutation, and one bore an H3 G33V mutation.
Therefore, in the quest to identify and interpret mutations, it is important to bear in mind that text mining can provide additional information complementary to that retrieved in standard database searches.
The arc2 mutation bears a single nucleotide substitution, which converts Ala-342 to Val in At2g28000.
43 LS mutation carriers bear an innate defect of their MMR machinery for which no cure is in sight.
Thus far, none of the identified mutations in PDAC, exemplified by K-RAS, the most frequent mutation, have borne therapeutic targets [ 44].
The mutation is borne by a specific TP53 haplotype characterized by the allele T of SNP rs9894946, located in the 3' non-coding region of the TP53 gene.
The TP53 mutation p.R337H, borne by a haplotype carrying the T allele of rs9894946 (SNP28) was detected in tumor and metastasis but not in non-cancer tissues of this 12-year-old patient.
Although the overall numbers of coding region mutations do not bear evidence of DT40-specific mutational processes, it was still worth investigating if any gene mutation could be found that significantly impacted the properties of the cell line.
