Sentence examples for mutation is well from inspiring English sources

If a person who has such a mutation is well, he or she may carry a mutation in a different gene that compensates for, or buffers, the harmful gene's effect.

Compound heterozygosity of R229Q, in trans, with a pathogenic NPHS2 mutation is well described causing SRNS [ 5, 7, 10– 10].

Although the H4G94A mutation is well tolerated by yeast, the H4G94P mutation is not, and leads to an altered cell cycle profile and inviability after two or three cell divisions.

This 17N mutation is well characterized in Ras and Rho small GTPases as conferring potent dominant-negative activity, and the main caveat with this reagent is that it could be overly strong by sequestering GEFs required for activation of other Rho family members in addition to CDC-42.

Additionally, while the K208N mutation is well defined and does not alter the backbone or side chain conformation at position 208, it is possible that removal of the charged Lys also increases the flexibility of the loop region, facilitating the new interactions made by the G202E mutation and E207 that stabilize this region in the presence of methanol.

This mutation is well-known and is associated with CJD in humans (Riek et al. 1998).

The N588K-hERG mutation is well-established to attenuate markedly the inhibitory actions of Class III but not Class Ia antiarrhythmic drugs (which depend less than do Class III IKr-selective drugs on channel inactivation to bind) [10,15,16].

Although the consequences of NF1 mutation are well understood in humans, its cell-biological function is still not well understood (Stephen et al., 2014).

Variability of phenotypes associated with mtDNA mutations is well recognized [ 13].

Worldwide variation in the distribution of BRCA1 and BRCA2 mutations is well recognised (Szabo and King, 1997).

The information about these mutations is well summarized and available through the International Registry of WS (http://www.wernersyndrome.org).org