Sentence examples for mutation is unusual from inspiring English sources

In addition, the disease caused by the mutation is unusual in that it begins at an especially early age.

The rpn12a-1 mutatisn is unusual because the T-DNA is inserted downstream of the RPN12a gene, and both the full-length RPN12a cDNA and a chimeric RPN12a-NPTII cDNA are produced.

Amplification of the MET gene (located on chromosome 7), like mutation, is unusual in invasive breast cancer: in a study of 155 patients, Carracedo and colleagues did not identify MET amplification at all (although 22% of tumours showed low-grade polysomy) [ 32].

Notably, in CRCs with EDMs, the spectrum and/or frequency of known driver mutations is unusual.

Although having multiple rare recessive mutations is unusual, the probability of having any rare recessive disease is increased by consanguinity.

6, 7 IDH1/IDH2 mutations are unusual in pediatric LGGs. 2 MT of LGG is rarer in children than in adults 2 (6.7% vs. 50%, respectively).

Mapping and complementation analysis indicated that three mutations are unusual alleles of msl1 and one maps to mle, two critical components of the dosage compensation complex.

It therefore seems reasonable to speculate that the mutation described herein is unusual in its effect, acting as a dominant gain of function mutation to cause AI, while the majority of LAMB3 mutations are knock-outs, causing no phenotype in carriers while manifesting as JEB with enamel defects in homozygotes.

The R46X mutation in SDHB is unusual because it predicts loss-of-function, it targets a classical tumor-suppressor gene, and it occurs in PBMCs.

Seizure suppression by gish loss-of-function mutations reported here is unusual in several respects.

The occurrence of 2 somatic SDHA mutations in the absence of a germline mutation is very unusual.