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Exact(8)
Mutation is thus limited to non-critical regions or would require multiple, simultaneous compensatory mutations that preserve function.
This mutation is thus sufficient to disrupt binding of BP1 protein to DNA.
This mutation is thus analogous to the well-characterized rod Pde6β rd1 mutation.
The sequence-dependent susceptibility to mutation is thus not considered to explain the periodicity of the diversity profile.
ASXL1 mutation is thus helpful for risk stratification of MDS patients with normal karyotype, which is categorized as an intermediate-risk cytogenetic group.
If BER fails, human mtDNA molecules containing the damage are usually degraded and base substitution (point mutation) is thus avoided [ 28].
Similar(52)
The E682K mutation was thus predicted to block the β′-site cleavage.
Considering the importance of berry size for wine quality, a fine mapping of the flb mutation was thus started for its molecular identification.
Analyses of variance to test the inheritance pattern of the IGF2 mutation were thus performed on 980 F2 animals (543 Dutch F2 and 437 French F2).
Genetic interaction (epistasis) between mutations is thus emphasized here, as often the adaptive phenotypes are more than a single mutation away, and if the intermediate step is deleterious, transversing to the potentially advantageous genotype can be impossible with single-step mutations.
The fraction of truly neutral mutations is thus n = n' - P 0).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com