Sentence examples for mutation is thought from inspiring English sources

In other countries, the frequency of this mutation is thought to be low.

This mutation is thought to arise from depurination of the DMBA-DNA adduct, followed by mis-replication across the unrepaired apurinic site (Schaaper, Kunkel, & Loeb, 1983; Strauss, 1985).

A BRCA2 mutation can increase risk by up to seven-fold, while a BRACA1 mutation is thought to double risk in men under 65 years old, says the study.

Because the mutation is thought to have popped up 700 years ago, long before AIDS appeared, biologists have assumed that the mutation confers resistance to a second pathogen, Yersinia pestis, which killed up to 40% of Europeans in the 14th century.

W11 is found in a family of South German Draft horses descending from a single white stallion, in which the causative mutation is thought to have originated.

The DHPS mutation is thought to be associated with failure of treatment and prophylaxis [ 15, 16].

Since this mutant encoded the N-terminal 119 amino acids protein fragment, which lacks both the intact MATH and BTB domains, this mutation was thought to be a null allele.

This mutation was thought to cause a major conformational change, particularly in the C-terminus which destroyed the reactivity to GAD65 of the human mAbs b78 and b96.11, and removed anti-GAD65 reactivity from most diabetes sera tested.

The presence of a BRCA 1 or BRCA 2 mutation was thought to influence locoregional and neoadjuvant treatment, but not adjuvant therapy.

Initially, given the observation of a nonsense mutation in CHRNA4, the gene encoding the neuronal nicotinic cholinergic receptor α4 subunit, segregating 13 with BFNS in a linked region of chromosome 20q, 14 this mutation was thought to be causal.

By contrast, others like the E578V mutation, are thought to alter the interaction of lamin A with other proteins, or interfere with protein-protein interactions (Supplementary Figure S1B) [ 19, 20].