Sentence examples for mutation is supposed from inspiring English sources
The mutation is supposed to have a severe effect in view of site-directed mutagenesis experiments and phenotypes of some patients.
It is questionable whether this rapid upsurge of anomalies fits a linear progression model, where mutations are supposed to occur sequentially and be retained due to positive selection.
This is corroborated by the fact that predicted null-alleles (e.g. frameshift and splicing mutations) are always compound heterozygous with a missense mutation, which is supposed to retain some residual activity.
Mutations of a conserved Leu residue that is supposed to protect the cluster from solvent were analyzed as well.
The second mutation very close to Ser172 was on Val 169, which is supposed to interact with GTP [34].
Considering the lack of familial history of malignancy in this case, it is supposed that the de novo p53 germline mutation occurred during early development.
It is supposed that indoor solar UVA exposure, which causes mutations, depletes vitamin D3 in the skin [ 93].
A point delay is supposed.
The panel is supposed to be heterogeneous.
Treatment efficacy is supposed to be high.
