Sentence examples for mutation is specifically from inspiring English sources

Each mutation is specifically associated with either a methionine or a valine polymorphic amino acid at codon 129, which can severely affect the type, the onset and the duration of the disease [4].

Further work is required to determine whether this mutation is specifically associated with risk of developing renal cancer.

In homozygous nub 1 flies (Additional file 1), expression of the nub-RD transcript is strongly reduced [ 20] and no Nub-PD protein is detected on immunoblots (Additional file 2B), whereas the Nub-PB protein is still expressed in the nub 1 flies, confirming that nub 1 mutation is specifically affecting the expression of the Nub-PD protein.

A recent global database analysis of the PB1-F2 prevealedevealed that the N66S mutation was present in only 3.8% of the H5N1 strains; however, the mutation was specifically found associated with the highly pathogenic strains.

TP53 is the most frequently mutated gene in cancer [ 104- 106] and TP53 mutations are specifically associated to tumor subgroups with distinct biological features, particularly in breast cancer [ 4, 5, 33, 107].

A second group of mutations was specifically designed to either increase or decrease the size and energy of the second encounter complex, but either way it did not affect kon.

Most of the mutations were specifically present in only one case, except G5783A, T4216C and A10149T.

To verify if the mutations were specifically affecting glycogen metabolism, we determined the trehalose content of cells from each strain.

These two studies demonstrate that independent DIA1R mutations are specifically associated with human XLMR, while the deletion studies implicate DIA1R deletion in autism-like syndromes and/or XLMR.

By contrast, the ΔLeu954 and Ala934Val mutations are specifically associated with DCM and have more modest effects on the cross-linking of actin filaments, especially the Ala934Val mutation [7].

For example, cancers that arise from BRCA1 mutations are specifically prone to PARP inhibitors.