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Progeny tests showed that the esk1-6 mutatisn is recessive (Table 2).
The mutation is recessive, and homozygous mutants first demonstrate abnormal rostro-caudal compressions at around 72 hpf (data not shown).
Mating unc-119 (ed3 ) with Drd homozygotes yielded wild-type F1 progeny, indicating the mutation is recessive.
In mice, the Dspp-null mutation is recessive and homozygotic null mice have a dentinogenesis imperfecta phenotype with incomplete mineralization of the dentin matrix [ 13].
The dpy-4 mutation is recessive and allows discrimination of self progeny from cross progeny on the basis of the Dumpy phenotype.
However, even a substantially deleterious mutation has a chance to segregate in the population, especially if the mutation is recessive [ 5].
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Results from both genetic analyses suggested that the ecr2-1 loss-of-function mutation was recessive and intergenic to ctr1-10.
The ndg-4 sa529 ndg-4 sa529 was backcrossed once to our wIII-type N2 to ensure the mutanton was recessive backcrossedrating the transheteronceoto ndg-4 mutants.
We found that the mtp5-1 mutation was recessive (data not shown) and restored iar1 root sensitivity not only to IAA-Ala, which we used to isolate the mutant, but also to IAA-Leu and IAA-Phe.
These studies, mostly based on mutation-accumulation experiments in flies, showed that the majority of deleterious mutations is recessive to their wild-type allele (Simmons and Crow 1977; Wilkie 1994; Houle et al. 1997; Chavarrias et al. 2001; Fry and Nuzhdin 2003).
Furthermore, most radiation-induced mutations are recessive; it can take many generations for two recessive genes to combine to form a child with a particular disease, like my specialty, cystic fibrosis.
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