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An intriguing possibility is that, for a certain subset of patients at least, rpoB mutation is preferred over other VISA mutations because of a beneficial secondary phenotype.
Similar(59)
Yet, Site 2 mutations are preferred by the TA pair in spite of the possible loss of function incurred by making changes at this site.
In summary, our method reported in this study is a valid alternative to be considered for generating Drosophila mutants with a reasonable efficiency and as little time and effort as possible, especially when the prevention of delayed mutation events is preferred to reduce the off-target effects and mosaicism.
We also show that, compared to ENU, EMS produces a similar or slightly higher fraction of non-synonymous mutations, which is preferred in chemical mutagenesis experiments for mutant screens.
If selection is preferred over mutation, the correlation (r) between the two quantities should be very high (r → −1).
Under the GCpref codon model, transversions to the same nucleotide consist of one mutation affecting fitness (C->A is unpreferred and A->C is preferred) and one neutral mutation (within a fitness class: T->A and G->C).
The latter is preferred.
More is preferred to less".
Amitriptyline is preferred.
Sometimes, complete anonimity is preferred.
Amoxicillin is preferred in Europe.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com