Sentence examples for mutation is predictive from inspiring English sources

In addition, TP53 mutation is predictive of poor response to chemotherapy and locoregional recurrence following radiotherapy.

Reduced expression of PTEN due to mutation is predictive of aggressive disease in human tumors [ 5].

We found no evidence that PIK3CA mutation is predictive of response in either ER-positive or ER-negative tumors.

The presence of a gyrA mutation is predictive of treatment failure with triple therapy for quinolones such as levofloxacin [ 45].

Another previous study of a small cohort of colorectal cancer patients reported that PIK3CA mutation is predictive of poor survival [ 23].

The presence of a KRAS mutation is predictive for resistance to anti-EFGR monoclonal antibodies (mAbs) in advanced colon cancer [ 13- 16].

Why would a PIK3CA mutation be predictive in some breast cancer cell types but not others?

To date, however, none of these markers has been introduced into routine clinical practice for the treatment of CRC, with the exception of recent and consistent evidence for Kras mutation being predictive for non-response to anti-EGFR treatment (Amado et al, 2008; Bokemeyer et al, 2008; Karapetis et al, 2008; de Roock et al, 2008; van Cutsem et al, 2008).

KRAS mutations are predictive markers for the efficacy of anti-EGFR antibody therapies in patients with metastatic colorectal cancer.

In contrast, whether BRAF and PIK3CA mutations are predictive of the efficacy of anti-EGFR therapy remains controversial [ 19- 22].

Activating EGFR mutations are predictive of response to EGFR inhibitors with reported response rates of upto 75%.