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Genomic and exomic sequencing data from the past several years have revealed that CREBBP and EP300 inactivation via mutation is more widespread and frequent than previously thought.
In phylogenetic analyses with clonal bacterial species, where mutation is more important than recombination, it is preferable to use concatenated sequences of the MLST loci rather than allelic profiles, because the magnitude of changes between alleles is lost in allelic profiles [41].
The frequency of the mutation in the csrS gene is higher than that in csrR (csrS mutation∶csrR mutation = 59∶19) (manuscript in preparation), suggesting the csrS mutation is more important in comparison with that of csrR in the clinical isolates regardless of emm genotypes.
It seems that this likely pathogenic missense mutation is more likely an incompletely penetrant allele.
This is equivalent to assuming that mutation is more frequent than recombination.
LST-G with BRAF mutation is more likely to be a sessile serrated adenoma.
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Medical experts said that those who carry that gene mutation are more likely than not to live disease-free.
The mutation has the opposite effect of the one found in Colombia: people with the mutation are more likely to retain sharp cognitive abilities well into their nineties.
Tabbies with the mutation are more often found in Europe, Dr. O'Brien said.
When growth curves were analyzed, the effect of the btuE mutation was more evident in aerobic conditions (Fig. S2A B).
The 101L-moPrP mutation was more susceptible to conversion to PrPres in the CAA than the wild type 101P-moPrP.
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