Sentence examples for mutation is maintained from inspiring English sources

The GarsC201R/+ females for this cross came from a colony in which the mutation is maintained by backcrossing to C57BL/6J mice.

The pde6c w59 mutation is maintained as heterozygotes and intercrossed to generate homozygous mutants.

In this colony, the Prop1df mutation is maintained on a heterogeneous genetic background.

With the exception of lethal selection or niche creation [ 11] experiments, most other studies have demonstrated that the fitness advantage conferred by a mutation is maintained across environments and conditions [ 9, 10].

pha-4 was needed for DR lifespan extension in our protocol, although DR was less effective in the smg-1 ts) smg-1 tsnd in which the pha-4 mutation is maintained (Panowski et al., 2007; Sheaffer et al., 2008) (23.2% lifespan increase in smg-1(ts) vs. 77.3% in WT from DR, and 44.6% vs. 77.3% from DD) (Fig. 2E,F, Tabackground

Mice carrying the Syktm1Tyb (referred to as Syk−) mutation were maintained as Syk+/− heterozygotes on the C57BL/6 genetic background [29].

Previously, we showed that loss of coilin was, somewhat surprisingly, homozygous viable when the mutation was maintained on an outbred CD-1 background [25].

The prop1 mutation was maintained on a heterogeneous background.

The Daam1 mutation was maintained in a C57BL/6 background, and the loop-tail mutant was on a CBA background.

Because of the limited fertility of homozygous PLCγ2−/− mice, the mutation was maintained in heterozygous form as described [ 26].

The fog-2 (q71) mutation was maintained during these introgressions by selecting for self-sterile hermaphrodites every few generations.