Sentence examples for mutation is lower from inspiring English sources

Not only are such viruses attenuated, but, because their rate of mutation is lower, they are less able to revert to a less faithful polymerase.

In Australia, the prevalence of the mutation is lower in 10 out of 1474 (0.68%) female breast cancer cases and one out of 736 (0.14%) controls (CHEK2 Breast Cancer Case-Control Consortium, 2004).

Despite the fact that a percentage of surgical and biopsy specimens that are described as harbouring a single heterozygous mutation is very high (35%), the proportion of cultured cancer cell lines supposedly carrying such a mutation is lower (10%).

Assuming SI8 30 sites are the least constrained class, the slower X evolution observed at these sites suggests either that these positions are weakly constrained, with more effective purifying selection on the X, or that the rate of mutation is lower on the X chromosome.

Data from [ 14]. *The chance of detecting a mutation is lower, because at least 15% of mutations are regulatory (ie they are not in the coding region of the gene that is the area tested), and the genetic screening methods are approximately 80% sensitive if sequencing is not used.

Moreover, recombination can reduce the mutational load, which is a deterministic process where deleterious mutations accumulate in the genome due to insufficient productivity of the fittest class [27], [68], [69] and background selection, where the probability of fixation of a beneficial mutation is lowered if it arises in a genetic background with low fitness [41], [70] [72].

The prevalence of PfDHFR triple mutation was lower in this study than in children who received IPT with SP+AQ or SP+AS in the two previous trials in the same area [3], [4].

The frequency of the BRAF p.Val600Glu mutation was lower (4.0%) but comparable to the reported frequency range of 4-18% in mCRC without KRAS codon 2 mutations [ 25, 27- 30].

Although the mean non-verbal IQ of the members of the large family carrying FOXP2 mutation was lower than of the unaffected members, non-verbal intellectual impairment could not be considered characteristic of the phenotype associated with this FOXP2 mutation (Lai, et al., 2001).

From these crosses we find the ratio of non-synonymous to synonymous mutations is lower in duplicated genes, which suggests that they are under greater purifying selection.

It is clear from our study that the sensitivity to EndoA-BAR mutations is lower in larvae than in adults.