Sentence examples for mutation is limited from inspiring English sources

Firstly, in terms of lineage size, the impact of mutation is limited within B1a B cells in the peritoneal cavity.

This might indicate that HJEB has not been transmitted into these breeds or that the allele frequency is very low and the c.2746delCA mutation is limited to BHM.

Exon 14 and exon 12 mutations differ by 2 main characteristics: the V617F mutation is limited to only one base change (G1846T) found in all subtypes of MPDs [6] as well as in splanchnic vein thrombosis [8] and some myelodysplastic syndromes patients [9].

However, the number of patients with a single CEBPA mutation is limited in our collection of patients, and larger series are needed to definitively assess its prognostic significance.

This could imply that while the functional impact of each individual mutation is limited, collectively they may mediate the signaling pathway activity through epistasis.

Till date, the clinical applicability of the KRAS mutation is limited, because there are no clinical associations strong enough for inclusion in clinical or therapeutic algorithms.

20 Another study demonstrated that the prognostic value of KRAS mutation was limited to patients with stage I/II CRC.

This coupling of DNA damage to phenotypic persistence may increase genetic diversity specifically in severe stress conditions, where diversity is beneficial but the ability to generate de novo mutations is limited.

While the characterization of the effects of most αB-crystallin mutations is limited, the effects of the R120G mutation on protein structure and chaperone activity have been extensively investigated [27] [30].

Thus, histopathological estimates of tumor-cell content are not predictive of the frequency of mutant alleles, while the ability to detect mutations is limited by the allele frequency but not by the tumor cell content.

The predictive power of the Koel mutations is limited and improvement restricted to a few years.