Sentence examples for mutation is initially from inspiring English sources
A probability of mutation is initially defined for each component.
This strategy does not exploit the repulsion between the mutation and FTL, but might be more suitable if the mutation is initially homozygous, and if it is easy to identify mut heterozygotes.
In the GeneSV system, each proposed codon mutation is initially characterized using 9 criteria, which are based on observed similarities with corresponding positions in genomic and protein sequences from available databases.
Assessment of clinical criteria for deciding whether the HNF1A and HNF4A gene mutations or the GCK gene mutation is initially tested is based on the judgement of experts in monogenic diabetes.
Lande showed that rapid evolution toward a new distant phenotypic optimum can be accomplished just as easily with polygenes as with a major mutation and, indeed, is more likely if the major mutation is initially rare or initially common but doomed to be lost.
This mutation was initially reported in one-third of hyperplastic benign breast lesions, although several recent studies failed to detect it in benign or malignant breast tissues.
NOD2 IVS8+158 gene mutation was initially reported to confer higher risk for Crohn's disease in Ashkenazi Jews [ 16].
This mutation was initially reported to promote the formation of toxic oligomers, and APP E693Δ transgenic mice lack extensive amyloid deposition [ 27, 30].
The p.G1186fsX1190 mutation was initially detected in apparent homozygosity in the CRC patient and in the control using primers described by Wu et al (1999).
The AKT1-E17K mutation was initially identified as a SNP, rs34409589, but in a recent publication it was found to be a somatic mutation and was found in 3 of 51 colon cancers [ 27].
The ROSA41 mutation was initially produced on a mixed 129S5, C57BL/6J strain background (Friedrich and Soriano 1991; Ross et al. 1998), but has since (as mentioned in the section Crosses) been backcrossed to a congenic C57BL/6J background.
