Sentence examples for mutation is immediately from inspiring English sources
The simplest case is a so-called "hard sweep" where a new mutation is immediately favorable and its increase in frequency carries a single haplotype (a window of sites around the selected polymorphism) to fixation in the population (Maynard Smith and Haigh 1974).
This becomes obvious if we imagine an organism in which most genes affect most traits and all mutations are immediately expressed in the phenotype.
This is because recessive X-linked mutations are immediately subject to selection in hemizygous males.
If weak deleterious effects are rare, then we expect that most deleterious mutations are immediately removed from the population.
Second, male-biased genes are expected to experience selection mainly in a male (hemizygous) genetic background where recessive X-linked mutations are immediately exposed to selection.
The molecular signature of selection depends strongly on whether new mutations are immediately favorable and sweep to fixation (hard sweeps) as opposed to when selection acts on segregating variation (soft sweeps).
This situation is best met in bacteria-phage interactions, which are usually characterized by large population sizes (i.e., high likelihood of the occurrence of favorable mutations), short generation times, and haploid genomes (i.e., new mutations are immediately expressed phenotypically) [ 11, 22- 24] (but see also [ 25]).
As the mutation site is immediately followed by NGR motif, we next tested whether the mutant endostatin has aminopeptidase N inhibitory activity.
The I424S mutation, which is immediately adjacent to the G425 site, but is buried in the hydrophobic core of the protein, was identified in the PRISM study from UK patients who consented to provide DNA samples for analysis.
Surya is immediately arrested.
For example, mutations could be immediately identifed as intergenic or intragenic, synonymous or non-synonymous etc. MAQ was used to call point mutations and compared to those made by SSAHA2.
