Sentence examples for mutation is fundamental from inspiring English sources

Protein side-chain mutation is fundamental both to natural evolutionary processes and to the engineering of protein therapeutics, which constitute an increasing fraction of important medications.

The location of the BRCA1 mutation is fundamental.

Published: October 17, 2013 The process of somatic mutation is fundamental to cancer development.

The mutation was fundamental: as a musician, Brabenec's saxophone and clarinet added new chromatics and textures - avant-garde jazz of the kind played by Soft Machine, Slavonic dances and klezmer rhythms changed the band's musical timbre, which had hitherto combined Velvet-esque rock with a distinctly Celtic edge to Jiri Kabes's violin.

The research on gene mutations is fundamental and family screening by clinical examination, chest X-ray, research of pulmonary shunting, and abdominal color Doppler sonography is absolutely necessary.

The detection of V600E BRAF mutation in melanoma is fundamental since here BRAF inhibitors represent an effective treatment.

Mutation is a fundamental process in tumorigenesis.

Mutation is a fundamental process in evolution and constitutes the raw material for natural selection.

Clearly, genetic mutation is a fundamental mechanism by which gene expression and function are altered, thereby giving rise to aberrant or cancerous behaviour in cells and tissues.

Somatic mutation is the fundamental mechanism by which cancer cells suborn these pathways (Stratton et al., 2009), notwithstanding the contributions of epigenetic changes, cues from the local microenvironment and germline genetic variation.

Identifying causes of rate heterogeneity as well as specific variables that affect underlying mutation and substitution rates is fundamental to understanding the mechanisms that cause evolution of DNA sequences (reviewed in [ 7]).