Sentence examples for mutation is first from inspiring English sources

An example of this may be an escape pattern where a primary mutation is first selected in context of a specific HLA allele, followed by a compensatory mutation at a secondary site [24], [35], [36].

In this assay, a mutant DNA with one base mismatch (C→G mutation) is first hybridised to a complementary DNA modified magnetic NP.

The AKT mutation was first identified as a cause of cancer in 2006, and several drug companies developed AKT inhibitors.

Furthermore, the true prevalence of nondeletional mutations and Thailand type (− THAI) deletion mutation were first reported in this study.

Prostate cancer containing the SPOP mutation was first discovered in 2011 by Weill Cornell Medicine researchers, who found that the malignancy has unique molecular features that characterize it as a distinct subtype.

In 2008, the R132H IDH1 mutation was first found in human glioblastoma multiforme [55].

To test this, the pdc2Δ519 mutation was first integrated by transformation and homologous recombination into the genome of the commercial EC1118 and the native Mab2C wine yeasts.

This process of evolution of activity by selection and mutation was first utilised ex vivo in phage display technology [2] and later using yeast or bacteria as vectors.

This mutation was first identified in families with aminoglycoside-induced deafness, and the ototoxic susceptibility was attributed to enhanced binding affinity to aminoglycosides of 1555A>G rRNA (Qian and Guan, 2009).

The K43R mutation in the gag gene was first detected at day 91 post screening and was fixed in the viral population at day 273 while the synonymous N323tc mutation was first detected at day 177 and fixed at day 670.

This mutation was first reported by Benson et al. who found similar electrophysiological defects in tsA201 cells [16].