Sentence examples for mutation is essentially from inspiring English sources

A mutation is essentially a genetic typo — an addition, deletion or alteration in the genomic sequence.

The smn-1 ok355 smn-1 ok355s essentially a null allele, albeit retaining progressively decreasing levels of mutation SMN-1.

Individuals from Li Fraumeni families who have an inactive p53 gene due to a germ-line mutation are essentially born with 'initiated' cells, and 90% of these individuals develop cancer by age 70 years.

Finding mutations is essentially a search for disorder.

BRAF mutations seem prevalent in MIN, whereas TP53 mutations are essentially found in CIN.

TE-generated mutations are essentially stochastic in nature, and many of them will have negative impact on survival.

Mutations are essentially random, occurring as independent events throughout the lifespan of an individual, potentially accelerated by exogenous carcinogens or DNA repair defects.

Notably, MDM2 amplification and p53 mutations are essentially mutually exclusive and, in the past few years, small-molecule antagonists of p53 MDM2 interaction as nutlins or MDM2 inhibitors have been developed.

β-Catenin missense mutations were essentially found at codons 41 and 45, identified as c.121 A>G or pThr-41-Ala (T41A), c.133T>C or pSer45Pro (S45P), and c.134C>T or pSer45Phe (S45F).

The phenotypic expression of the c.833T>C mutation in heterozygotes is essentially unknown [ Guttormsen et al., 2001; Sperandeo et al., 1996a].

In summary, despite the diversity of this mutation range, the optimum mutation rate was essentially determined by population size and mutation effects (Note: even larger orders of ranges gave very rough results and are not shown).