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The game has three steps: (1) construction of a dichotomous diagram by submission of the parental DNA to successive copies in which the chance of mutation is dictated by special roulettes.
The timing of the second mutation is dictated by the formation rate of the particular mutation and the size of the colony.
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In addition, the substitution process is dictated mainly by mutation in species with a low Ne.
The actual level of ongoing autophagy in the tumour cells is dictated by genetic mutations but also influenced by the epigenetic regulation of gene expression [ 65, 103].
As will be described shortly, the reason for the different location and double insertion is sequence related and we argue that it is dictated by a single point mutation.
As melanomas are more genetically heterogeneous than first thought, it is likely that 'personalised' combination therapies will need to be developed, whereby patient therapy is dictated by the constellation of mutations found within their tumors.
The particular pathway taken is dictated stochastically by the frequency of the several mutation types and the growth improvement caused by each new mutation.
The most difficult part may be finding the scaling function, but once it is found, the global dynamics is dictated by a very simple condition on the mutation rates, given in Corollary 1.
This maximum value is dictated by the number of cells in the population as well as the mutation rate giving rise to new cell types.
The timetable is dictated by British law.
"A lot is dictated by finance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com