Sentence examples for mutation is confined from inspiring English sources

Hence, the prognostic value of the BRAF mutation is confined to the MSS/left-sided tumors.

In this study, the definition of a genetic mutation is confined to the protein-truncating mutation and the missense mutation, which have a confirmed association to disease.

This latter mutation was confined to the tumor.

All but one mutation were confined within three distinct regions.

In our study, BRAF mutation was confined to PTC and was not detected in benign lesions.

However, one mutation was confined to intron 11; therefore the biologic significance of this mutation is unknown[ 11].

To rule this out, we obtained a second allele, tm3223, where the mutation was confined to dnj-14 alone.

All but one mutation was confined within three distinct regions, suggesting that they might be under selective pressure.

Positional cloning work, in which the position of the mutation was confined to a narrow chromosomal interval by classical mapping methods and all sequences within this interval were examined for mutations, revealed that the lesion altered the structure of a mammalian homolog of Toll – TLR4 [ 32].

Three of the detected variants were novel and all mutations were confined to exon 4 of INF2, a regulatory region responsible for 90% of all changes reported in FSGS due to INF2 mutations.

Until recently, routine screening of tumours for mutations was confined to low- and medium-throughput platforms.