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A mutation is any variant that is rare (the classic definition is 1% frequency in a population), whereas a polymorphism is a more frequent variant.
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All plasmids were sequenced to confirm if the designed mutation is present, without any other unwanted mutation.
The probability of an oncogenic mutation is vanishingly small for any particular cell.
However, the virulence phenotype supposedly associated with the mutation is not observed to any proportional extent.
Because only a single mutation is involved, testing by any number of simple and inexpensive molecular genetic methods is possible.
Any new mutation is then directly annotated in Vector NTI and considered in any subsequent gel run.
This mutation is silent.
While a mutation is defined as 'any change in the DNA', most work has focused on studying 'Single Nucleotide Variations' (SNVs).
Whilst attractive, the downfall of ideas oriented around beneficial mutations is that any advantage to sex vanishes in the absence of directional selection.
However, we see no strong evidence of any specific mutation being unusually enriched among any of the variants.
No mutation was found in any of the samples.
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