Sentence examples for mutation is addressed from inspiring English sources

To our knowledge, this is the first study in which the difference in family history between patients with unexplained MSI-positive tumours and patients with a recognised germline mutation is addressed.

New understanding of the DNA break-dependent stress-induced mutation mechanism is addressing a key part of this long standing dilemma.

The problem is addressed by inducing the transposition during anther culture so that selected mutations can be transmitted and then regenerated to a homozygous state.

The frequency and risk estimates for BRCA2 mutation carriers was addressed by several studies, most comprehensively it was recently evaluated in a large cohort by our group (Kote-Jarai et al, 2011), which reported an ∼8.6-fold increased risk of PrCa for BRCA2 mutation carriers.

The problem of embryonic or perinatal lethality, particularly with animals carrying combinatorial mutations, can be addressed using two powerful approaches.

The concept of random distributed and frequency dependent fitness of mutations can be addressed by evolutionary game theory [ 21], which considers evolutionary processes under frequency dependent selection [ 22].

Moreover, the potential for deleterious gene expression changes resulting from promoter mutations or copy number variation has been addressed in relatively few studies (10, 108– 108).

Mutation testing has been addressed for test data generation only in the work of Henard et al. (2014).

The study of the evolution of mutation rates has been addressed theoretically [13], [18] [21], and using digital organisms [17].

The onset of CVD relevant to this mutation has not been addressed.

Finally, once the level of resistance and patterns of neutral genetic differentiation are characterized across the landscape, the more challenging question of how resistance has arisen— that is, through selection on standing genetic variation, or due to novel mutations across populations can be addressed.