Sentence examples for mutation is acquired from inspiring English sources

By reconstructing the exact pattern of chromosomal rearrangements, he and colleagues found it could not be explained by the standard process in which one mutation is acquired after another in a protracted series.

Studies of familial PV have shown that the JAK2 V617F mutation is acquired somatically [39], [40], but have suggested that mutation in another gene may precede the JAK2 mutation in PV.

The advantage of combining two drugs becomes insignificant if the number of mutations that confer resistance to only one drug is very low (Figure 2b), or if the rate at which the cross-resistance mutation is acquired is relatively high.

We study the dynamics of tumor growth as one additional driver mutation is acquired.

The first mutation is acquired through the germline while the second is usually acquired via loss of heterozygosity, a common mechanism of tumor suppressor gene inactivation in general.

There are data suggesting that this point mutation probably leads to complete abolition of PU.1 activity (22), and that mice carrying a deletion of the other allele might develop AML relatively soon after the mutation is acquired.

This mutation was acquired in the second CSI period and presumably does not affect the function of the neighboring domains.

Additionally, no BRAFV600E mutation was acquired in three patients with an initial homozygous wild-type BRAF genotype (Table 1).

This value can be interpreted as the number of times the considered mutation was acquired not earlier than the resistance was acquired.

The M184V mutation was acquired later because only 12.5% of K65R/K103N viruses carried the M184V mutation at the first time point during treatment failure.

Analogously, the coloring induced by a given binary mutation profile will contain the set of nodes in which the mutation was acquired.