Sentence examples for mutation is accommodated from inspiring English sources

The 1.63 Å (1 Å = 0.1 nm) structure of the variant demonstrates that the mutation is accommodated at the dimer interface to generate an enzyme with substantially the same activity and specificity as wild-type caspase-3.

In previous studies designed to increase the primary structure symmetry within the hydrophobic core of human acidic fibroblast growth factor (FGF-1) a combination of five mutations were accommodated, resulting in structure, stability and folding kinetic properties similar to wild-type (despite the symmetric constraint upon the set of core residues).

We show that the S116R mutation in human FGF-1 is accommodated with no perturbation of biophysical or structural properties, and is therefore an attractive mutation with which to elucidate the functional role of phosphorylation.

In the event that one residue of such an interacting pair mutates, the effect of the mutation can be accommodated by the 'correlated' mutation of its interacting partner.

In the closed state, the V99W mutation can be accommodated between TM3a and TM1/TM2, possibly with TM1/TM2 being moved in the direction found in the open state, which would be consistent with the GOF properties in electrophysiological assays.

All mutations are within an RMSD value of 1.2 Å (Figure 1D), indicating that the mutations can be accommodated by simple flexible deformation of the protein.

For those samples with mutations in known DNA repair genes, any global increase in mutation rate will be accommodated by our model's sample-specific background rate estimation (see Section 2.3.2).

An alanine-to-aspartic acid mutation can probably be accommodated in this water exposed loop.

The support staff is accommodating and cheerful.

Introgression experiments of Drosophila simulans siII mtDNA type into the sympatric population siIII nu background did not show a difference in catalytic properties of mitochondria, indicating that some naturally occurring mutations in mtDNA can be accommodated by different nu background and mt nu interaction (Pichaud et al. 2012).

However, it is still possible that the helical geometry introduced by the G>A mutation in the organellar ribosome could be accommodated without a major deleterious effect.