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Overexpression of hh in the background of a trol mutation is able to rescue the premature differentiation phenotype.
The recessive rga mutation is able to partially suppress phenotypic defects of the Arabidopsis gibberellin (GA) biosynthetic mutant ga1-3.
In this view, it seems that D9 mutation is able to partially suppress the effects of the D4 mutation, at least for what concerns swimming.
In line with this interpretation, the P4270L mutation is able to completely abrogate the interaction with NPHP1-SH3 both in GST pull-down assays and in the co-immunoprecipitation studies.
As S protein carrying the L857-F mutation is able to induce cell cell fusion, but losses the activity when F857 was mutated back to L, it suggests that induction of cell cell fusion is an essential step in adaptation/selection of IBV to cultured mammalian cells.
In this regard, a T790M mutation is able to enhance the GTP affinity and block TKI binding to the tyrosine kinase domain of EGFR [ 29].
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In Africa, those who carried the mutation were able to leave 10 times more progeny, creating a strong selective advantage.
Consistent with this, we found that the chat-1 ok1681) chat-1 ok1681able to suppress the axon regeneration defect of ced-7(n2094) mutation(Fig. 5b and Supplementary Table 1).
While this leukodystrophy results in demyelination, GPs cultured with this mutation were able to produce normal OLs in culture.
Interestingly, the flc-3 mutation was able to suppress the non-flowering phenotype of the brm-1 mutant plants (Figure 3A).
Co-immunoprecipitation experiments in transfected cells demonstrated that ApoER2 carrying the R774L mutation was able to bind Pafah1b2 and Pafah1b3, unlike the wild type receptor (Fig. 3B).
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