Sentence examples for mutation involving a from inspiring English sources

Some kinds of melanoma have a mutation involving a gene called BRAF; others don't.

Moreover a combined mutation involving a membrane-bound protein and unknown soluble factors may be present.

Nineteen and 17 patients had a mutation involving a splice factor gene or an epigenetic regulator, respectively.

Although the biological consequence of this mutation is still under investigation, given the high frequency of this mutation involving a functionally important, conserved residue, it is likely relevant for tumourigenesis.

In July 2007, Carpten et al published a very interesting study on the AKT1 gene in Nature, where they detected a novel transforming mutation involving a glutamic acid (E) to lysine (K) substitution at amino acid 17 (E17K) in the pleckstrin homology domain of the AKT1 gene.

The data indicated that the entire fetal genome complement is present in cf-DNA in maternal plasma, and that this can be mined to show minute details such as mutations involved in β-thalassaemia; surprisingly, the study correctly discerned that the fetus had inherited the paternal codon 41/42 mutation, involving a CTTT deletion, but not the maternal −28A→G mutation.

This mutation involves a lysine to methionine substitution at position 29 and is present at a gene frequency of 30% in African populations [31] [33].

Nevertheless, analyzing the structure in detail, this residue is found exposed, and the mutation involves a charge inversion from a negatively charged glutamic acid to positively charged lysine.

The most common (>90%) second-site mutation involves a C→T change at nucleotide 2369 in exon 20, which results in substitution of methionine for threonine at position 790 (T790M).

The first mutation involved a deletion of an adenine in the OL at position 5182.

This mutation involves a substitution of an aspartic acid (D) for the glycine (G) at the 13th position.