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Another mutation involved codon 820, an infrequently mutated residue but one that has been previously reported (Pignon et al, 1997).
The KRAS mutation involved codon 12 in 12 (57%) of the mutated cases, codon 13 in 6 (29%), codon 61 in 2 (10%) and codon 146 in one (5%).
Prenatal testing is possible, however, if a parent has Marfan's and the particular mutation involved is identified.
There is defintely a mutation involved, but whether it is inherited or not is less clear as more cases are examined.
Since, even with this relatively low level of synteny, as the relationship is called, dogs have proved useful in the study of some human diseases, the researchers hope that the high-synteny horse could be similarly illuminating.They tested this by looking for the as-yet unknown genetic mutation involved in what is called the leopard complex.
Likewise, there are several drugs available to treat colorectal cancer, although their efficacy differ across the genetic mutation involved in the development of the disease.
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The mutation involves the deletion of part of a gene on the surface of cells.
Some kinds of melanoma have a mutation involving a gene called BRAF; others don't.
Mutation involving gatekeeper residues (such as V654a and T670I) influence both the structure and the catalytic activity of the enzyme.
At the protein level, each mutation involves the replacement of three to four consecutive residues with alanine.
But this mutation involves an amino acid exchange.
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