Sentence examples for mutation into this from inspiring English sources

Introduction of a 3-bp substitution mutation into this ATF4-binding site essentially eliminated the PTH response.

After introduction of a point mutation into this seed sequence the construct is no longer repressed by injection of miR-10 (figure 2C).

Incorporation of the T63S mutation into this background (Kcv(TS), Figure 8A) reduced sensitivity to barium further and causes a change that when compared with the wild-type is in line with that seen in the Kir2.1 background (∼12 fold relative to wild type).

Introducing the E54D mutation into this construct (MNV/SVD1/E54D) had no effect on NS boundary cleavage.

For reasons not understood, it proved impossible to move the nanE mutation into this background on its own.

We introduced the Sharkey mutation into this TALEN scaffold, as Sharkey is known to enhance the DNA cleavage activity of FokI in both homodimeric and heterodimeric ZFN architectures (Guo et al., 2010; Doyon et al., 2011).

To test the functional consequences of the mutated F2 in enhancer blocking we introduced this mutation into the F1F2 enhancer blocking construct.

In order to investigate the molecular and physiological basis of HHD in the patient carrying missense mutation A528P, located in the putative nucleotide binding domain of the molecule, site-directed mutagenesis was employed to introduce this mutation into the wild-type ATP2C1 (hsequenceequence.

We introgressed this mutation into the Columbia background in order to facilitate its genetic analysis with other flowering time mutants that are in the Columbia background and then used this introgressed line (lov1-4) to investigate LOV1 function.

To introduce this mutation into the GNPTAB construct, 48 bp primers were used.

An expression construct incorporating this mutation into the ZIC3 cDNA has previously been reported to produce no protein (Ware et al., 2004).