Sentence examples for mutation into account from inspiring English sources

Nowadays, it is considered critical to take viral mutation into account during the development of treatment strategies.

A more realistic tumor growth model should take resistance to drug, such as may occur through mutation, into account.

Thus, selection schemes against BFT should not only take the status at the IGF2 mutation into account but also genotypes at other QTL in the region.

An association of the infection/colonization by B. cepacia with ACE gene D/I polymorphism was identified for patients without taking the CFTR mutation into account, OR: 4.509 (1.513 - 10.89), and for patients with one CFTR mutation identified to class I, II or III, OR: (1.43 - 40.38), for the D/D genotype (Table  4).

This is in line with the emerging evidence of the importance of the PI3K pathway as a possible target for therapy strategies in 20 30% of SCC 9. When taking additional alterations, such as PIK3CA amplification and AKT1 mutation, into account this further corroborates the role of PI3K pathway 9, 14, 16– 16.

Differences on average lifespan between the two most extreme lines, FVB and C57BL/6J, represent around 25% of the average lifespan of the C57BL/6J strain, highlighting the importance of taking the genetic background of this mutation into account, and highlighting that the loci responsible might be points for therapeutic intervention.

Forsim can simulate pedigrees and take evolutionary processes such as natural selection, mutation, and population demographics—into account.

Thus, there is an extensive dataset to take compensatory base mutations into account for the prediction of novel ncRNA candidates.

30 Many clinical trials taking EGF-R mutations into account have now been published, 31 but economic analyses are still needed.

Because there is no conclusive evidence for the function of any of these missense mutations yet, we did not take these missense mutations into account in the subsequent analysis exploring the effect of RT.

The main limitations of these tools stem from the fact that they rely solely on haplogroup-defining patterns of mutations derived from the phylogenetic tree and they lack a database of real haplotypes that takes private mutations into account.