Sentence examples for mutation inhibited the from inspiring English sources

We also surveyed some agronomic characters of the tcm5 and WT plants and found that, under field condition, the grain and panicle number per plant (Additional file 1: Figure S2) was significantly decreased, showing that the mutation inhibited the plant growth in tcm5 mutants.

In fact, the Co2+ transport assay revealed that the T305L mutation inhibited the transport ability of TmCorA, which is a clear indication that the position of Thr remains unchanged during the operation of the gate.

Interestingly, we found that the A809V/rmGlu5 mutation inhibited the ability of VU0357121 to shift the glutamate concentration−response curve, whereas the response to VU0357121 was not altered by the F585I/rmGlu5 mutation.

To confirm that the F32E mutation inhibited the binding of PRH to TLE in the context of full-length PRH protein in vivo, we carried out co-immunoprecipitation experiments with Myc-tagged PRH and FLAG-tagged TLE1.

However, having established that the M705V mutation affected the binding of both CHIP and the cSti1 in a predictable manner, we next tested the binding of Tah1 and, as expected, we found that the M705V mutation inhibited the binding of Tah1 (Kd=13±1.7 μM) relative to wild-type protein (Kd=0.78±0.06 μM; Figures 1a and 6e).

New evidence suggests that IDH1 mutation inhibits the growth of glioma cells via GSH inhibition and generation of reactive oxygen species (ROS) [ 32].

PMD is a progressive and fatal disorder in which a genetic mutation inhibits the normal growth of myelin, a protective material that envelopes nerve fibers in the brain.

Thus, neither the M605I nor the A727V mutation inhibits the interaction between MuSK and Lrp4 or MuSK and Tid1.

This demonstrates that the △3 mutation inhibits the IRES ribosome complex from using eEF2 to facilitate stable ac-tRNA delivery.

These results collectively demonstrate how the oncogenic KRAS mutation inhibits the tumor suppressor FBW7, thus revealing an important function of KRAS mutations in promoting pancreatic cancer progression.

In contrast, the F585I/rmGlu5 mutation inhibits the PAM activity of CPPHA but has no effect on responses to VU-29 activity (14).