Sentence examples for mutation indicating a from inspiring English sources

CLN3 transcription was not affected by T36 mutation, indicating a posttranslational mechanism.

Also in the present case, the pyloric gland adenoma and the BilIN-3 harbored a KRAS codon 12 mutation, indicating a possible metaplasia-dysplasia-carcinoma sequence with a common tumourigenesis.

The incidences of prostate cancer, cervix cancer and nonmelanoma skin cancer are elevated for FDRs of early-onset breast cancer cases without a BRCA mutation, indicating a possible association between these cancers and early-onset breast cancer.

Considering the geographical distribution in which the --SEA has been found in only Thai, Filipino, Vietnamese, and Chinese populations [ 23], our phylogenetic network indicates that the --SEA appears to come from an Asian-specific haplotypic background, is consistent with the localized distribution of this mutation, indicating a recent origin of the deletion.

The comparison of the effect in enzymes with mutation indicated a positive correlation with increased genetic damage, after 24 and 48 h of exposure for all concentrations tested.

The E200K mutation indicated a significant reduction in glycosylation in comparison to the wild-type, which could affect to the conformational changes in prion protein [ 23].

5) The authors propose that the reduced τc values for the charge reversal mutation indicates a shift to more open conformations.

The screenings yielded 5 AsCslF6 mutations and 6 AsPAL1 mutations, indicating a mutation frequency of one mutation in 38 kb and one mutation in 38.5 kb, respectively.

Just nine sites carry only silent mutations indicating a preponderance of changes with effects on polypeptide sequence.

Genetic studies show that a gain-of-function mutation of dpy-17 suppresses phenotypes of dpy-31 mutations, indicating a genetic interaction between the two.

In addition, a few PZ-resistant strains with no PZase activity did not have pncA mutations, indicating a potential regulatory gene of pncA that may have acquired a mutation.