Sentence examples for mutation including in from inspiring English sources

In this study we mutated the ecsAB genes of S. aureus and characterized the changes in transcriptome profile, phenotype and functional properties of staphylococci in relation to this mutation including in vivo evaluation of virulence.

For instance, typical rates of mutation, including in salmonids, are too low to generate large fitness effects over such short time-periods.

It has been suggested that GLP functional diversity has arisen via sequential gene duplication events, followed by mutation, including in flanking regulatory regions, giving rise to diversity in temporal and spatial gene expression patterns [ 25].

In addition, patients carrying a p.V600K mutation included in the BRIM-3 study showed response to this inhibitor [ 7].

F227C is another example of a mutation included in the IAS-USA panel that is not likely to be significant as a transmitted mutation, as F227C confers "minor" resistance to rilpivirine, a drug that is as yet unavailable in India.

Importantly, several of these mutations, including in TP53 [ 62] and BRCA1 [ 14], are preferentially associated with the metastasis-prone basal subtype.

The procedure traditionally used for the search of drugs or therapeutic mutations includes in vitro experiments, designed to prevent the aggregation of model proteins, which are then complemented with cellular toxicity studies in vivo, slowing down the finding of solutions.

We updated PatternLab to take advantage of the new Comet-PEFF search engine that enables identifying post-translational modifications and mutations included in neXtProt's PSI Extended FASTA Format (PEFF) metadata.

SIFT predictions for mutations included in our training set are shown in Supplementary Material, Table S9C.

Importantly, all PGRN mutations included in this study were clear pathogenic loss-of-function mutations, leading to haploinsufficiency.

However, the mutations included in the LRP are completely absent or very rare in all non-European ancestries.