Sentence examples for mutation in such from inspiring English sources

Although various cytogenetic abnormalities are commonly reported, the association between constitutional trisomy 21 and AMKL has been of particular interest, because of the near universal presence of GATA1 mutation in such cases.

Rather, they are conserved because a mutation in such a buried residue would tend to perturb the architecture.

Mutation in such genes can result in reduced viability [ 58] and genes involved in egg development should reflect these characteristics.

The chances of finding a mutation in such a small region is less than in larger regions studied for the other two species.

It may therefore seem remarkable that a mutation in such a ubiquitously expressed gene could produce a defect that appears to be selective for this particular stage of T cell development.

It is also reported that m.1555A>G can cause hearing loss even in the absence of aminoglycoside exposure, although this tends to be less severe and of later onset, 3 4 and that nuclear-encoded modifier genes may increase penetrance of the mutation in such cases.

"It is a terrific tour de force to be able to detect those mutations in such small quantities," said Dr. Kenneth Offit, a geneticist at Sloan-Kettering.

Mutations in such genes often result in MS in different forms, e.g. knockout mutation of CAP1, which encodes l-arabinokinase, resulted in collapsed abnormal pollens (Ueda et al. [2013]), and microsporeless anthers resulted from null mutations of MSCA1 in corn (Chaubal et al. [2003]) and MIL1 in rice (Hong et al. [2012]).

Mutations in such elements have previously been implicated in human diseases [33].

Animals with mutations in such genes are of particular interest as they exhibit a male heterozygous phenotype, that can affect the phenotype of their wild type progeny.

In 1914, Boveri cited aneuploidy as a cause of cancer, but the subsequent discovery of oncogenes and tumor suppressor genes led to a new theory, wherein the accumulation of mutations in such genes was the cause of malignant transformation [20].