Sentence examples for mutation in particular from inspiring English sources
In the age of personalised medicines, antisense oligonucleotides can sometimes be designed to target and bypass or overcome a patient's genetic mutation, in particular those lesions that compromise normal pre-mRNA processing.
The inclusion of the lpr mutation in particular enhances disease severity, by triggering lymphoproliferative pathology.
One MyD88 mutation in particular, in which Leu is changed to a proline residue, accounts for approximately a third of all cases of DLBCL [ 20].
The effect of genetic mutation in particular TFBSs on the methylation state of CpGis has recently been refined by Lienert et al. [ 27].
Artificial T > C substitutions at the position of the exon 13 p.V654A mutation, in particular, led to a lower sensitivity, independent from the source of the material.
Exon 11 mutations (including point mutations, in-frame deletions and insertions) are the most common KIT mutations; the L576P mutation in particular is found in approximately one third of these melanomas [166,179,180].
While standard testing could not find mutations in particular genes in 10 of the 22 patients, the experimental procedure let researchers identify the abnormal genes in all the patients.
They can identify mutations in particular genes, and they can monitor the activity of lots of genes at the same time showing a doctor which genes in a tumour are busier than they should be, and which are less busy.
Incomplete repair of DPX can lead to the formation of mutations, in particular chromosome mutations and micronuclei (MN) in proliferating cells.
The identification of single-base mutations in particular genes plays an increasingly important role in medical diagnosis and prognosis of genetic-based diseases.
The field of premature aging has garnered immense interest also because of the emerging number of premature aging disorders observed in humans, with a significant proportion of the syndromes originating from mutations in particular genes.
